Circadian rhythm disturbances in depression

Circadian rhythm disturbances in depressiony

Objective The aim of this article is to review progress in understanding the mechanisms that underlie circadian and sleep rhythms, and their role in the pathogenesis and treatment of depression. Methods Literature was selected principally by Medline searches, and additional reports were identified based on ongoing research activities in the authors’ laboratory. Results Many physiological proces...

Addressing circadian rhythm disturbances in depressed patients.

Desynchronisation of normal circadian rhythms, including the sleep-wake rhythm, is common in major depressive disorder (MDD). The association between sleep disturbances and depression has long been recognised. Disturbed sleep is a diagnostic criterion for MDD, and insomnia commonly precedes the onset of symptomatic mood disorders. Disruptions of the sleep-wake cycle (sleep architecture and timi...

[Sleep and circadian rhythm disturbances in schizophrenia].

AIM In this study we investigated sleep and circadian rhythm, functioning and psychopathological symptoms in patients with schizophrenia. We looked for answers to the following questions: What percentage of patients with schizophrenia after a therapeutic process in the daily psychiatric ward suffers from insomnia and excessive daytime sleepiness? What factors influence the functioning of patien...

Circadian Rhythm and Bipolar Disorder Impact of Circadian Rhythm Disturbances in Bipolar Disorder

Jet lag, circadian rhythm sleep disturbances, and depression: the role of melatonin and its analogs.

Traveling through several time zones results in a constellation of symptoms known as jet lag. These include reduced alertness, daytime fatigue, loss of appetite, reduced cognitive skills, and disruption of the sleep/wake cycle. In susceptible air travel passengers, jet lag may exacerbate affective illness and result in psychiatric morbidity. Dysregulation of circadian rhythms and melatonin secr...